Proteolysis‐targeting chimeras in drug development: A safety perspective - Moreau - 2020 - British Journal of Pharmacology - Wiley Online Library
PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics | Oncogene
Delineating the role of cooperativity in the design of potent PROTACs for BTK | PNAS
A suite of mathematical solutions to describe ternary complex formation and their application to targeted protein degradation by
Design, synthesis, and biological evaluation of small molecule PROTACs for potential anticancer effects | Medicinal Chemistry Research
Accelerating PROTAC drug discovery: Establishing a relationship between ubiquitination and target protein degradation
An AURKA PROTAC cocktail relieves the hook effect. A) Scheme depicting... | Download Scientific Diagram
PROTAC-mediated ternary complex formation and hook effect. The hook... | Download Scientific Diagram
Development of BromoTag: A “Bump-and-Hole”–PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins | Journal of Medicinal Chemistry
A suite of mathematical solutions to describe ternary complex formation and their application to targeted protein degradation by
Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs - ScienceDirect
Frontiers | From Conception to Development: Investigating PROTACs Features for Improved Cell Permeability and Successful Protein Degradation
Biomolecules | Free Full-Text | Central Nervous System Targeted Protein Degraders
Pharmaceutics | Free Full-Text | A Mechanistic Pharmacodynamic Modeling Framework for the Assessment and Optimization of Proteolysis Targeting Chimeras (PROTACs)
The Power of PROTACs - LifeSensors
PROTACs: Current Trends in Protein Degradation by Proteolysis-Targeting Chimeras | BioDrugs
a) PROTAC-mediated ternary complex formation and Hook effect as a... | Download Scientific Diagram
Delineating the role of cooperativity in the design of potent PROTACs for BTK | PNAS
The importance of cellular degradation kinetics for understanding mechanisms in targeted protein degradation - Chemical Society Reviews (RSC Publishing) DOI:10.1039/D2CS00339B
Frontiers | From Conception to Development: Investigating PROTACs Features for Improved Cell Permeability and Successful Protein Degradation
PROTAC® Ubiquitination Assays - LifeSensors
Proteolysis‐targeting chimeras in drug development: A safety perspective - Moreau - 2020 - British Journal of Pharmacology - Wiley Online Library
Pharmaceutics | Free Full-Text | Estrogen Receptor-α Targeting: PROTACs, SNIPERs, Peptide-PROTACs, Antibody Conjugated PROTACs and SNIPERs
Frontiers | From Conception to Development: Investigating PROTACs Features for Improved Cell Permeability and Successful Protein Degradation
a) PROTAC-mediated ternary complex formation and Hook effect as a... | Download Scientific Diagram
